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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules

‘It had been just a make a difference of picking up a book on mobile biology and starting to read. I'd come from a globe of extremely-substantial vacuums, cryostats and quantum phenomena, and now I was Doing the job at place temperature with molecular biology kits.

Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.

That is a aspiration of mine and we established to work using a delectable dose of naivety. This can be a thing that will most likely yield stunning brings about the for a longer time expression, but that doesn't matter. You should not only want to operate over the concerns of tomorrow, but will also around the inquiries with the working day following tomorrow.’

Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,

MATLAB codes for details processing can be obtained at . Julia codes utilized for numerical simulation are offered at .

Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation

‘Yes, I have an understanding of individuals have been astonished at time. At the end of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t master Significantly any more. The field went additional into the appliance facet, how you might combine nanotubes into Digital circuits.

But carbon nanotubes have remained a analysis subject of considerable interest to many. In truth, the outlook on applying carbon nanotubes to build simple equipment, in parts for instance radio-frequency electronics, digital electronics and flexible electronics, continues to be shiny.

FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial cell division

Later on we spoke all over again briefly simply because Dekker felt that our discussion of his faith speedily turned purely philosophical, Whilst it also concretely aids him in his operate.

Visualization of unstained DNA nanostructures with Highly developed in-focus transmission electron microscopy methods

Strong-state nanopores have verified for being a incredibly functional probe for one-molecule Investigation of DNA. I'll describe a few of cees dekker our modern results – especially DNA knots – along with our attempts to increase the capabilities of solid-point out nanopores even further more, during the way of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.

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